The first case study of the Women4Climate initiative was developed between May and August 2018 in San Francisco. The study highlights issues of gender, race, affordability and mobility associated with bicycling as a low carbon transportation solution in the SoMa neighborhood and examines the bike lanes’ climate action benefits as well as other health, safety, economic and environmental benefits and the barriers to cycling that remain, especially for women, as well as the strategies that could help overcome these barriers.